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Mapping the brain

Published On 08/08/2014

How does the human brain work and how does each part work together to help us speak, let us move, give us memories? What happens when seizures disrupt brain activity and brain tumors grow? How does the mind adjust? The Clinical Neurosciences team is answering these questions and challenging the gold standard by using noninvasive brain mapping to make surgical decisions for children with epilepsy and brain tumors.

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le Bonheur Children's Hospital: Epilepsy Case Study

Epilepsy case study

A 17-year-old girl’s brain showed no signs of abnormalities, but she had focal and generalized seizures. Uncontrolled by medication, her medical team considered surgery to remove her left temporal lobe. Noninvasive brain mapping technology gave her and her team confidence surgery was the right option.A

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Le Bonheur Children's Hospital: Brain Tumor Case Study

Brain tumor case study

A 42-year-old woman was in a car accident as a result of a seizure. MRI reveals a tumor in her posterior frontal lobe. It was biopsied, but the team chose not to resect at the time. Seizures were controlled by medication for seven years. Technology gave her team confidence they could resect the tumor.

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Complete functional imaging at Le Bonheur Children's Hospital provides more information for better outcomes.

Functional mapping

Functional brain imaging is used to record sensory, motor and cognitive functions happening in the brain. The goal is to identify areas of abnormal activity and the areas responsible for specific normal functions. Hear our team explain how functional MRI (fMRI), magnetoencephalography (MEG) and transcranial magnetic stimulation (TMS) work and help guide surgical decisions.

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Grace's story

After six years of seizures, 17-year-old Grace Hugueley’s parents were afraid to leave her home alone. Brain surgery to remove part of her left temporal lobe was her last hope. But Grace wanted to be sure she’d be able to play the piano after surgery. Noninvasive brain mapping technology gave her medical team the confidence that Grace would be the same girl, just without the seizures. Hear Grace’s family share their story.

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Joan Han, MD, pediatric obesity specialist

After hearing concerns from families, Le Bonheur leaders assembled a multidisciplinary taskforce including family members to create better ways for families and caregivers to share information. The plan paid off. Since the taskforce’s formation, Le Bonheur has seen a significant increase in its inpatient experience scores, landing in the 90th percentile among children’s hospitals.

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Genetic factors: Researchers look for innate immunity factors to guide urinary tract infections treatment

Nephrologist David Hains, MD, is trying to learn why some kids with vesicoureteral reflux have repeat urinary tract infections while other kids with reflux can go through childhood without infection. His theory: genetic factors, especially those in the urinary tract, are game changers for some patients.

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A national early intervention program pairing nurses with first-time, low-income mothers reduces preventable deaths among both children and their mothers, according to a study published in JAMA Pediatrics. The results from the Memphis Nurse Family Partnership study were announced this summer at Le Bonheur, which has served 410 families through the program.

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